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Clinical monitoring use case: Cystic Fibrosis with the National Health System (UK)

 
 
 
 
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How NHS worked with Sonde

Royal Papworth Hospital in Cambridge, UK and Cambridge University under direction of Professor Andres Floto started running Project Breathe in 2019. Project Breathe is evaluating whether home monitoring can improve the way we care for people with CF. Sonde is teaming up with Project Breathe to provide Sonde’s respiratory app for daily voice sample collection. In this phase, vocal biomarkers will be analyzed by the joint research team without using the scores clinically, to evaluate their potential to further improve care management. 100-200 people with CF will get access to the Sonde app and submit daily voice samples in addition to their established home monitoring under Project Breathe.

 
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The Benefits

 
 

100-200 participants from Royal Papworth Cystic Fibrosis clinic

Add-on to an ongoing initiative that collects daily telemetry from patients

Goal is to demonstrate potential for early detection of the onset of pulmonary exacerbations

 
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Vocal biomarkers could provide a unique monitoring approach in cystic fibrosis because:

Patients in cognitive behavioral therapy

High frequency of data collection (daily)
for extended periods (12+ months)

20 pilot participants

Simple and non-invasive:

Captures patient’s voice only

Depression, anxiety, adjustment disorder

No equipment needed:

Uses patient’s own smartphone

 
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